Enhancing accuracy in automated liquid handling with VeriPlate

VeriPlate system
© CSEM

Revolutionizing laboratory automation achieving precision and compliance

In the highly regulated world of laboratories, precision and accuracy in pipetting are essential to ensure every experiment’s success and reliability. The VeriPlate system, developed by Hamilton and CSEM, sets a new benchmark in laboratory automation by verifying the accuracy and precision of pipetting systems. VeriPlate uses microfluidic technology, which allows precise manipulation of tiny amounts of liquid. It also uses optical image analysis, a technique that employs light to examine and measure these liquids. By combining these technologies, VeriPlate efficiently evaluates the accuracy and consistency of the dispensed liquid volumes by analyzing the liquid-filled microfluidic channels.

CSEM’s role: pioneering innovations with microfluidic technology

CSEM, a pioneer in microfluidics, designed the microfluidic plate at the heart of VeriPlate. This patented technology verifies the precise manipulation of liquids on a miniature scale, which is essential for modern laboratory applications. The microfluidic plate meets the stringent requirements of pharmaceutical, diagnostic, and life sciences laboratories. By reducing discrepancies in liquid handling, CSEM’s innovation ensures consistency in high-throughput screenings and complex assays. These microfluidic plates are designed to handle large sample volumes, making them ideal for high-demand laboratory environments. “This is a significant advancement in the safe use of automated liquid handling systems,” says Dr. Christoph Jung, Vice President of Robotics at Hamilton Bonaduz.
  

Hamilton’s expertise: ensuring pipetting excellence

Hamilton has leveraged its advanced robotic and optical imaging capabilities to commercialize VeriPlate as part of its Hamilton Pipetting Excellence Program. By combining Hamilton’s cutting-edge automation technologies built into the robotic system with ongoing field services, the program equips labs with the tools to effectively monitor, check, and verify the quality of the pipetting process from start to finish. “This program focuses on enhancing laboratory productivity and accuracy by integrating state-of-the-art technologies into routine workflows. Hamilton’s automated systems ensure that every pipette delivers consistent results, eliminating human error and variability,” notes Dr. Jung. Detailed test reports generated by VeriPlate allow laboratories to identify and address discrepancies quickly, reducing downtime and costs. “VeriPlate is an essential part of Hamilton’s Pipetting Excellence Program and will have a substantial impact on our business and sales,” adds Dr. Jung.

Transforming laboratory workflows with VeriPlate

Samantha Paoletti, Head of Research & Business Development, Life Science Technologies at CSEM, explains the benefits of the VeriPlate system: “The microfluidic plate ensures uniform liquid distribution, a critical factor in sensitive assays. This technology minimizes variability, making it indispensable for laboratories focused on drug discovery, diagnostics, and genomics. Hamilton’s expertise in optical imaging allows the VeriPlate system to analyze and validate pipetting accuracy in real time. This feature ensures that results are reproducible and compliant with regulatory standards. The entire system is designed with user-friendliness in mind. Even operators with minimal training can perform routine tests efficiently, ensuring smooth integration into existing workflows. By reducing experimental repetitions and optimizing liquid-handling processes, VeriPlate helps laboratories save on reagent costs and operational expenses.”
  

Collaborative success shaping the future of laboratory automation

The partnership between CSEM and Hamilton exemplifies how shared expertise can lead to groundbreaking solutions. This collaboration has advanced laboratory automation and underscores the importance of precision technologies in addressing modern challenges. CSEM’s microfluidic expertise and Hamilton’s robotic integration have created a solution tailored to the needs of today’s laboratories.

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