Non-invasive. 24/7. Clinically proven.
CSEM’s patented optical blood pressure monitoring (oBPM) technology enables 24/7, non-invasive tracking of blood pressure (BP) without a cuff, providing comfortable and effective BP management. Using photoplethysmography (PPG) sensors and advanced pulse wave analysis (PWA) algorithms, oBPM delivers real-time measurements with clinical-grade accuracy across multiple body sites.
Validated against invasive gold-standard measurements and meeting ISO 81060-2 accuracy and precision targets, CSEM’s cuffless oBPM technology offers a proven solution for 24/7 systolic, diastolic, and mean BP monitoring. With applications ranging from acute intraoperative settings to long-term home monitoring, it provides comprehensive cardiovascular insights. Whether you are developing wearables, medical devices, or telemedicine solutions, our technology allows you to leapfrog traditional R&D cycles. In partnership with CSEM, device manufacturers and healthcare providers can rapidly bring cuffless BP monitoring to their users, giving them a competitive edge in cardiovascular care.
CSEM’s cuffless BP monitoring solution has been rigorously validated in clinical settings, with particular emphasis put on its ability to track BP variations (trending ability). Leading innovators in digital health have already adopted our oBPM technology, demonstrating compelling real-world applications across diverse form factors.
Each company has a unique approach, and we help take it further by combining accuracy with real-world usability. This collaborative drive, combined with growing clinical acceptance, is rapidly moving us toward a future where managing BP is as easy as glancing at your watch or phone, thereby improving clinical outcomes as well as hypertension diagnosis and management.
By being cuffless, oBPM shows a much higher patient acceptance and adherence than conventional cuff-based BP monitors, allowing 24/7 uninterrupted monitoring over weeks and months. Uninterrupted data collection reveals more representative and accurate circadian BP pattern assessment—from crucial nocturnal dips to morning surges, to activity- or treatment-related BP fluctuations—that traditional intermittent cuff-based BP monitors simply cannot detect through isolated readings. These data-driven insights enable better-informed treatment decisions, leading to increasingly personalized and effective hypertension management strategies.
Leveraging advanced PWA algorithms, our oBPM technology extracts accurate BP values from PPG signals, and has been clinically validated across diverse use cases, including:
While it can track BP changes in mmHg without any calibration, oBPM requires initialization through a single-point calibration, typically using a cuff-based BP device, to estimate absolute BP values. Our study in subjects followed up over a 4-month period post-calibration demonstrates that oBPM maintains good accuracy and precision at all times (bias within ±5 mmHg, standard deviation (SD) < 8 mmHg).
CSEM is actively advancing oBPM through longitudinal studies that evaluate long-term accuracy and clinical relevance. Current research includes:
In-lab investigations of hypotensive events in patients with autonomic nervous system disorders are also ongoing, with the goal of allowing evaluation of hemodynamic instability symptoms in real-life conditions for improved treatment guidance using a wearable PPG sensor.
Additionally, research in contactless BP estimation using remote PPG via camera-based systems are underway, demonstrating strong potential for inconspicuous monitoring in a preliminary feasibility study.
Our research also focuses on calibration-free BP estimation using machine learning models. These innovations aim to eliminate the need for initial cuff-based calibration while maintaining clinical accuracy. Deep learning architectures, including convolutional and transformer-based models designed to capture long-range dependencies and improve robustness under dynamic conditions for BP estimation from PPG, have shown promising results in intraoperative settings.
All of these ongoing clinical studies and research projects are driving oBPM even further, improving BP monitoring in clinical use cases and patient populations where a strong clinical need for a cuffless 24/7 BP solution remains to this day unmet.
Our scientists and engineers are actively advancing the frontiers of cuffless BP monitoring through ongoing clinical studies and technological innovations. If you are interested in collaborative research opportunities or would like to discuss how our latest findings could benefit your specific application, we welcome the opportunity to explore potential partnerships that will drive the field forward together.