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Non-invasive monitoring of pulmonary artery pressure from timing information by EIT: experimental evaluation during induced hypoxia
Monitoring of pulmonary artery pressure (PAP) in pulmonary hypertensive patients is currently limited to invasive solutions. We investigate a novel non-invasive approach for continuous monitoring of PAP, based on electrical impedance tomography (EIT), a safe, low-cost and non-invasive imaging technology. EIT recordings were performed in three healthy subjects undergoing hypoxia-induced PAP variations. The pulmonary pulse arrival time (PAT), a timing parameter physiologically linked to the PAP, was automatically calculated from the EIT signals. Values were compared to systolic PAP values from Doppler echocardiography, and yielded strong correlation scores (r=-0.94, +- 0.07) for all three subjects. Results suggest the feasibility of non-invasive, unsupervised monitoring of PAP.

Authors: Martin Proença, Fabian Braun, Josep Solà, Andy Adler, Mathieu Lemay, Jean-Philippe Thiran and Stefano F Rimoldi

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